SFRP1 (C-term) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC
Recommend Dilution	Peptide ELISA: 1/1000 (Detection Limit). Immunohistochemistry on Paraffin Sections: 3-6 µg/ml. In paraffin embedded Human Kidney shows vesicular staining in epithelial cells of PCT.
Reactivity	Bovine, Human, Mouse
Host	Goat
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to the C-terminus of Human SFRP1 (NP_003003.3).
Specificity	Recognizes Secreted Frizzled-related Protein 1 (SFRP1) at C-term.
Formulation	Tris saline, pH~7.3 State: Aff - Purified State: Liquid purified IgG fraction Stabilizer: 0.5% BSA Preservative: 0.02% Sodium Azide
Concentration	lot specific
Purification	Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	secreted frizzled related protein 1
Database Link	Entrez Gene 6422 Human UniProt ID Q8N474
Background	SFRP1 (also known as FRP, FRP1, SARP2, Secreted Apoptosis-related Protein 2, Secreted Frizzled-related Protein and Secreted frizzled-related protein 1) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP1 and SFRP5 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP1 is expressed in several human tissues, with the highest levels in heart.
Synonyms	SFRP-1, FRP-1, FRP1, FRP, SARP2, SARP-2
Reference Data

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