WNT3 (315-329) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA: 1/2000. Immunohistochemistry on Paraffin Sections: 3.75 µg/ml. Western Blot: 1/2000, 1 - 3 µg/ml.
Reactivity	Canine, Human, Mouse, Rat, Bovine, Bat, Chicken, Equine, Monkey, Porcine, Xenopus, Zebrafish
Host	Goat
Clonality	Polyclonal
Immunogen	Synthetic peptide from an internal region of human WNT3
Specificity	This antibody detects WNT3 (Internal).
Formulation	Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide State: Aff - Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Immunoaffinity chromatography
Conjugation	Unconjugated
Storage Condition	Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name	Wnt family member 3
Database Link	Entrez Gene 22415 MouseEntrez Gene 24882 RatEntrez Gene 7473 Human UniProt ID P56703
Background	The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product.
Synonyms	Proto-oncogene protein Wnt-3, INT4, INT-4
Reference Data
Protein Families	Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways	Basal cell carcinoma, Hedgehog signaling pathway, Melanogenesis, Pathways in cancer, Wnt signaling pathway

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