TRF2 (TERF2) Goat Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
Reactivity	Human, Bovine, Bat, Canine, Equine, Monkey, Porcine
Host	Goat
Clonality	Polyclonal
Immunogen	Synthetic peptide from human TERF2 / TRF2
Specificity	This antibody reacts to Telomeric Repeat Binding Factor 2 (TERF2).
Formulation	Tris saline buffer, pH 7.3 containing 0.5% BSA and 0.02% sodium azide State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Immunoaffinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	telomeric repeat binding factor 2
Database Link	Entrez Gene 7014 Human UniProt ID Q15554
Background	Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and plays a central role in telomere maintenance and protection against end-to-end fusion of chromosomes. In addition to its telomeric DNA-binding role, required to recruit a number of factors and enzymes required for telomere protection, including the shelterin complex, TERF2IP/RAP1 and DCLRE1B/Apollo. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection.
Synonyms	TRBF2, TRF2
Reference Data
Protein Families	Transcription Factors

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