IL17D Rabbit Polyclonal Antibody
CAT#: AP23788PU-S
IL17D rabbit polyclonal antibody, Aff - Purified
Size: 100 ug
Conjugation: Biotin
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CNY 3,910.00
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Specifications
Product Data | |
Applications | ELISA, WB |
Recommend Dilution | Sandwich ELISA: To detect Human IL17D by Sandwich ELISA (using 100μl/well antibody solution) a concentration of 0.5-2.0 μg/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with Biotinylated Anti-Human IL17D (AP23788BT-N or AP23788BT-S) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of recombinant Human IL17D. Western Blot: To detect Human IL17D by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant Human IL17D is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions. |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Highly pure recombinant Human IL-17D. |
Specificity | Recognizes Interleukin-17D / IL17D |
Formulation | PBS, pH 7.2 without preservatives State: Aff - Purified State: Lyophilized (sterile filtered) purified Ig fraction |
Reconstitution Method | Centrifuge vial prior to opening. Restore in sterile water to a concentration of 0.1-1.0 mg/ml. |
Purification | Affinity Chromatography employing an immobilized Human 17D matrix |
Conjugation | Unconjugated |
Storage Condition | Store the lyophilized antibody at -20°C. Following reconstitution it is stable for two weeks at 2-8°C. Frozen aliquots are stable for 6 months when stored at -20°C. Avoid repeated freezing and thawing. |
Gene Name | interleukin 17D |
Database Link | |
Background | The originally described IL-17 protein, now known as IL-17A, is a homodimer of two 155 amino acid chains, secreted by activated T-cells and acts on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region and differ from one another in their N-terminal segments and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as disulfide-linked homodimers. IL-17D has the ability to stimulate the production of IL-6, IL-8 and GM-CSF and inhibits hemopoiesis of myeloid progenitor cells in colony forming assays. |
Synonyms | IL-17D, IL27, Interleukin-27 |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein |
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