Cryptochrome I (CRY1) (551-555) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western blot: 1/500-1/1000.
Reactivity	Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Peptide sequence around aa.551~555 (S-Q-G-S-G) derived from Human CRY1.
Specificity	This antibody detects endogenous level of total CRY1 protein.
Formulation	Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl and 50% glycerol State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.02% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography using epitope-specific peptide
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	60 kDa (Predicted)
Gene Name	cryptochrome circadian clock 1
Database Link	Entrez Gene 12952 Mouse UniProt ID Q16526
Background	Blue light-dependent regulator of the circadian feedback loop. Inhibits CLOCK|NPAS2-ARNTL E box-mediated transcription. Acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. Has no photolyase activity. Capable of translocating circadian clock core proteins such as PER proteins to the nucleus. May inhibit CLOCK|NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL.
Synonyms	CRY1, PHLL1
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Circadian rhythm - mammal

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