MMP1 (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Immunohistochemistry on Paraffin Sections: 1/50. Western Blot.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	MMP1 antibody was raised against a synthetic peptide from near C-terminal of human MMP-1 protein.
Specificity	This antibody reacts to the C-term of MMP1.
Formulation	10 mM PBS, pH 7.4 containing BSA as stabilizer and sodium azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Purification	Immunoaffinity chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	matrix metallopeptidase 1
Database Link	Entrez Gene 4312 Human UniProt ID P03956
Background	MMP1 is a Metallopeptidase M10A type protease. MMP1, also known as collagenase, is a secreted protein. Collagenase is the only enzyme able to initiate breakdown of the interstitial collagens, types I, II, and III. The fact that the collagens are the most abundant proteins in the body means that collagenase plays a key role in the remodeling that occurs constantly in both normal and diseased conditions.
Synonyms	Interstitial collagenase, Matrix metalloproteinase-1, Fibroblast collagenase, MMP1, CLG
Reference Data
Protein Families	Druggable Genome, Protease, Secreted Protein
Protein Pathways	Bladder cancer, Pathways in cancer, PPAR signaling pathway

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