IDO1 Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, PEP-ELISA, WB
Recommend Dilution	Peptide ELISA: 1/128000 (Detection limit). Western Blot: 0.5-1.5 µg/ml. Approx 50kDa band observed in Human Lymph Node, Spleen and Placenta lysates (calculated MW of 45.3kDa according to NP_002155.1). Immunohistochemistry on Paraffin Sections: 4-6 µg/ml. In paraffin embedded Human Colon shows textured staining in the cytoplasm of absorptive cells.
Reactivity	Canine, Human, Mouse, Rat
Host	Goat
Clonality	Polyclonal
Immunogen	Synthetic peptide (CVLANWKKKDPNK) from the internal region of Human IDO1 (NP_002155.1).
Specificity	This antibody recognizes INDO / IDO.
Formulation	Tris saline, pH~7.3 State: Aff - Purified State: Liquid purified Ig fraction Stabilizer: 0.5% BSA Preservative: 0.02% Sodium Azide
Concentration	lot specific
Purification	Antigen Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	indoleamine 2,3-dioxygenase 1
Database Link	Entrez Gene 3620 Human UniProt ID P14902
Background	IDO is expressed by a wide variety of tissues and IDO can be upregulated by interferon gamma. IDO modulates levels of the amino acid tryptophan, which is vital for cell growth, but is also involved in the suppression of the immune response. Reports suggest that IDO is involved in the suppression of the immune response to tumours and blocking the IDO pathway may be a potential target for immunotherapy.
Synonyms	IDO1, IDO, INDO, Indoleamine 2,3-dioxygenase 1, EC=1.13.11.52, Indoleamine 2,3-dioxygenase, IDO, Indoleamine-pyrrole 2,3-dioxygenase
Reference Data

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