ALG2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western blotting (0.2 - 1.0 µg/ml)
Reactivity	Bovine, Canine, Human, Mouse, Porcine, Rat, African clawed frog
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide directed towards the C terminal of human ALG2
Formulation	State: Aff - Purified State: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purification	Purified using peptide immunoaffinity column
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing.
Gene Name	ALG2, alpha-1,3/1,6-mannosyltransferase
Database Link	Entrez Gene 56737 MouseEntrez Gene 313231 RatEntrez Gene 85365 Human UniProt ID Q9H553
Background	ALG2 is a member of the glycosyltransferase 1 family. It acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii).This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii).
Synonyms	CDGIi; FLJ14511; hALPG2; NET38
Reference Data
Protein Pathways	Metabolic pathways, N-Glycan biosynthesis

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