A1CF (C-term) Rabbit Polyclonal Antibody
CAT#: AP50047PU-N
A1CF (C-term) rabbit polyclonal antibody, Aff - Purified
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CNY 6,160.00
货期*
5周
规格
Cited in 3 publications. |
Specifications
Product Data | |
Applications | FC, IHC, WB |
Recommend Dilution | ELISA: 1/1000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100. Flow Cytometry: 1/10 - 1/50. |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 397-427 amino acids from the C-terminal region of human ACF |
Specificity | This antibody reacts to APOBEC1 complementation factor. |
Formulation | PBS containing 0.09% (W/V) sodium azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Affinity chromatography on Protein A |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Gene Name | APOBEC1 complementation factor |
Database Link | |
Background | Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. |
Synonyms | A1CF, ACF, ASP |
Note | Molecular Weight: 65202 Da |
Reference Data |
Citations (3)
The use of this Antibodies has been cited in the following citations: |
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APOBEC1 complementation factor facilitates cell migration by promoting nucleus translocation of SMAD3 in renal cell carcinoma cells
,Xia, H;Liu, Y;Xu, L;Mao, H;Zhou, Q;Xie, Y;,
In vitro cellular & developmental biology. Animal
,PubMed ID 34002283
[A1CF]
|
A1CF-promoted colony formation and proliferation of RCC depends on DKK1-MEK/ERK signal axis
,Ni, D;Yi, Q;Liu, J;Hu, Y;Lv, T;Tan, G;Liu, Y;Xu, L;Xia, H;Zhou, Q;Xie, Y;,
Gene
,PubMed ID 31881249
[A1CF]
|
A1CF-Axin2 signal axis regulates apoptosis and migration in Wilms tumor-derived cells through Wnt/β-catenin pathway
,Ni, D;Liu, J;Hu, Y;Liu, Y;Gu, Y;Zhou, Q;Xie, Y;,
In Vitro Cell. Dev. Biol. Anim.
,PubMed ID 30825095
[A1CF]
|
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