BCL3 (Center) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, IF, IHC, WB
Recommend Dilution	ELISA: 1/1000. Western blotting: 1/1000. Immunohistochemistry on Paraffin Sections: 1/50-1/100. Flow Cytometry: 1/10-1/50. Immunofluorescence: 1/10-1/50.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 249~277 amino acids from the Center region of Human BCL3
Specificity	This antibody recognizes Bcl-3.
Formulation	PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) Sodium Azide
Concentration	lot specific
Purification	Protein A Chromatography followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	46800 Da
Gene Name	B-cell CLL/lymphoma 3
Database Link	Entrez Gene 602 Human UniProt ID P20749
Background	BCL3 is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers.
Synonyms	BCL3, BCL4, D19S37
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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