FYB1 (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1/1000. Western Blot: 1/100-1/500.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 645-675 amino acids from the C-terminal region of Human FYN-binding protein
Specificity	This antibody recognizes Human FYN-binding protein (C-term).
Formulation	PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein A column, followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	FYN binding protein
Database Link	Entrez Gene 2533 Human UniProt ID O15117
Background	FYB acts as an adapter protein of the FYN and LCP2 signaling cascades in T cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2.
Synonyms	FYN-T-binding protein, FYB-120/130, p120/p130, SLAP-130, SLAP130
Note	Molecular Weight: 85387 Da
Reference Data
Protein Families	Druggable Genome

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