KAT2A (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, WB
Recommend Dilution	ELISA: 1/1000. Western Blot: 1/100-1/500. Flow Cytometry: 1/10-1/50.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 806-837 amino acids from the C-terminal region of Human KAT2A / GCN5L2
Specificity	This antibody recognizes Human and Mouse KAT2A / GCN5L2 (C-term).
Formulation	PBS containing 0.09% (W/V) Sodium Azide as preservative State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	lysine acetyltransferase 2A
Database Link	Entrez Gene 14534 MouseEntrez Gene 2648 Human UniProt ID Q92830
Background	KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).
Synonyms	Histone acetyltransferase KAT2A, Histone acetyltransferase GCN5, HsGCN5, HGCN5, Lysine acetyltransferase 2A, STAF97
Note	Molecular Weight: 93926 Da
Reference Data
Protein Families	Transcription Factors
Protein Pathways	Notch signaling pathway

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