KCNJ11 (N-term) Rabbit Polyclonal Antibody

CAT#: AP52309PU-N

KCNJ11 (N-term) rabbit polyclonal antibody, Aff - Purified



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CNY 6,160.00


货期*
5周

规格
    • 400 ul

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Specifications

Product Data
Applications FC, WB
Recommend Dilution ELISA: 1/1000.
Western Blot: 1/100-1/500.
Flow Cytometry: 1/10-1/50.
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between 6~35 amino acids from the N-terminal region of human KCNJ11
Specificity This antibody recognizes Human and Mouse KCNJ11 (N-term).
Formulation PBS containing 0.09% (W/V) Sodium Azide as preservative
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Protein A column, followed by peptide affinity purification
Conjugation Unconjugated
Storage Condition

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Gene Name potassium voltage-gated channel subfamily J member 11
Background ATP-sensitive potassium (K(ATP)) channels are found in endocrine cells, neurons and both smooth and striated muscle, where they play an important role in controlling insulin secretion and vascular tone, and protect neurons under metabolic stress. Kir6.2 is a member of the inward rectifier potassium channel family, which is characterised by a greater tendency to allow potassium flow into the cell rather than out of it. It associates with the sulphonylurea receptor SUR1/ABCC8 to form a subfamily of K(ATP) channels that, when mutated or misregulated, are associated with forms of hyperinsulinemic hypoglycemia, neonatal diabetes, or pre-disposition to type 2 diabetes mellitus. Provided below are standard protocols that you may find useful for product applications.

Synonyms KCNJ11, Inward rectifier K+ channel Kir6.2, IKATP
Note Molecular Weight: 43541 Da
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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