KCNJ11 (N-term) Rabbit Polyclonal Antibody
CAT#: AP52309PU-N
KCNJ11 (N-term) rabbit polyclonal antibody, Aff - Purified
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CNY 6,160.00
货期*
5周
规格
Specifications
Product Data | |
Applications | FC, WB |
Recommend Dilution | ELISA: 1/1000. Western Blot: 1/100-1/500. Flow Cytometry: 1/10-1/50. |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 6~35 amino acids from the N-terminal region of human KCNJ11 |
Specificity | This antibody recognizes Human and Mouse KCNJ11 (N-term). |
Formulation | PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Protein A column, followed by peptide affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Gene Name | potassium voltage-gated channel subfamily J member 11 |
Database Link | |
Background | ATP-sensitive potassium (K(ATP)) channels are found in endocrine cells, neurons and both smooth and striated muscle, where they play an important role in controlling insulin secretion and vascular tone, and protect neurons under metabolic stress. Kir6.2 is a member of the inward rectifier potassium channel family, which is characterised by a greater tendency to allow potassium flow into the cell rather than out of it. It associates with the sulphonylurea receptor SUR1/ABCC8 to form a subfamily of K(ATP) channels that, when mutated or misregulated, are associated with forms of hyperinsulinemic hypoglycemia, neonatal diabetes, or pre-disposition to type 2 diabetes mellitus. Provided below are standard protocols that you may find useful for product applications.
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Synonyms | KCNJ11, Inward rectifier K+ channel Kir6.2, IKATP |
Note | Molecular Weight: 43541 Da |
Reference Data |
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