KCNQ5 (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1/1000. Western Blot: 1/100-1/500.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 780-809 amino acids from the C-terminal region of human KCNQ5
Specificity	This antibody recognizes Human and Mouse KCNQ5 (C-term).
Formulation	PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein A column, followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	potassium voltage-gated channel subfamily Q member 5
Database Link	Entrez Gene 226922 MouseEntrez Gene 56479 Human UniProt ID Q9NR82
Background	This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents. They are also inhibited by M1 muscarinic receptor activation. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms	Potassium voltage-gated channel subfamily KQT member 5, Voltage-gated potassium channel subunit Kv7.5, Potassium channel subunit alpha KvLQT5, KQT-like 5
Note	Molecular Weight: 102179 Da
Reference Data
Protein Families	Druggable Genome, Ion Channels: Potassium, Transmembrane

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