Midkine (MDK) (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	ELISA: 1/1000. Western Blot: 1/100-1/500. Immunofluorescence: 1/10-1/50. Immunohistochemistry on Paraffin Sections: 1/50-1/100.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 113-143 amino acids from the C-terminal region of Human Midkine
Specificity	This antibody recognizes Human and Mouse Midkine (C-term).
Formulation	PBS containing 0.09% (W/V) Sodium Azide as preservative State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	midkine (neurite growth-promoting factor 2)
Database Link	Entrez Gene 17242 MouseEntrez Gene 4192 Human UniProt ID P21741
Background	Midkine is a retinoic acid-responsive, heparin-binding growth factor expressed in various cell types during embryogenesis. It promotes angiogenesis, cell growth, and cell migration. Midkine is also expressed in several carcinomas, suggesting that it may play a role in tumorigenesis, perhaps through its effects on angiogenesis (summary by Reynolds et al., 2004 [PubMed 15197188]).
Synonyms	MK, MDK, MK1, NEGF2, Neurite outgrowth-promoting protein
Note	Molecular Weight: 15585 Da
Reference Data
Protein Families	Druggable Genome, Secreted Protein, Transmembrane

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