PDZK1 (Center) Rabbit Polyclonal Antibody

CAT#: AP53250PU-N

PDZK1 (Center) rabbit polyclonal antibody, Aff - Purified



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CNY 6,160.00


货期*
5周

规格
    • 400 ul

Product images

Specifications

Product Data
Applications IHC, WB
Recommend Dilution

ELISA: 1/1000.
Western Blot: 1/100-1/500. 
Immunohistochemistry on Paraffin Sections: 1/10-1/50.

Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between 195-224 amino acids from the Central region of human PDZK1
Specificity This antibody recognizes Human PDZK1 (Center).
Formulation PBS containing 0.09% (W/V) Sodium Azide as preservative
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Protein A column, followed by peptide affinity purification
Conjugation Unconjugated
Storage Condition

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Gene Name PDZ domain containing 1
Background A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. May function to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism. May be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function (By similarity).
Synonyms PDZK1, NHERF3, NHERF-3, NHE-RF3, NaPi-Cap1, CAP70
Note Molecular Weight: 57129 Da
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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