PTP gamma (PTPRG) (Center) Rabbit Polyclonal Antibody
CAT#: AP53515PU-N
PTP gamma (PTPRG) (Center) rabbit polyclonal antibody, Aff - Purified
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CNY 6,160.00
货期*
5周
规格
Specifications
Product Data | |
Applications | WB |
Recommend Dilution | Western blot: 1/100-1/500. |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide - KLH conjugated - corresponding to the central region (between 670-700aa) of human PTPRG / PTPG |
Specificity | This antibody recognizes PTPRG / PTPG. |
Formulation | PBS with 0.09% (W/V) Sodium azide State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Purified through a Protein A column followed by peptide affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Gene Name | protein tyrosine phosphatase, receptor type G |
Database Link | |
Background | The protein encoded by the PTPRG gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene. |
Synonyms | HPTPG; H_RG317H01.1; PTPG; R-PTP-GAMMA; RPTPG |
Note | Molecular Weight: 162003 Da |
Reference Data | |
Protein Families | Druggable Genome, Phosphatase |
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