ZCRB1 (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Immunohistochemistry on paraffin sections: 1:10~50. ELISA: 1:1;000. Western blot: 1:100~500.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 183-212 amino acids from the C-terminal region of human ZCRB1
Specificity	This antibody detects ZCRB1 (C-term).
Formulation	PBS with 0.09% (W/V) sodium azide State: Aff - Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Protein A column followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name	zinc finger CCHC-type and RNA binding motif containing 1
Database Link	Entrez Gene 67197 MouseEntrez Gene 85437 Human UniProt ID Q8TBF4
Background	Pre-mRNA splicing is catalyzed by the spliceosome. U12-type spliceosome binds U12-type pre-mRNAs and recognizes the 5' splice site and branch-point sequence. U11 and U12 snRNPs are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron. The protein encoded by this gene contains a RNA recognition motif. It was identified as one of the protein components of U11/U12 snRNPs. This protein and many other U11/U12 snRNP proteins are highly conserved in organisms known to contain U12-type introns. These proteins have been shown to be essential for cell viability, suggesting the key roles in U12-type splicing.
Synonyms	MADP-1; MADP1; MGC26805; RBM36; U11/U12-31K; ZCCHC19
Note	Molecular Weight: 24592 Da
Reference Data

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