ERK2 (MAPK1) pTyr205/222 Rabbit Polyclonal Antibody

CAT#: AP55841PU-N

ERK2 (MAPK1) pTyr205/222 rabbit polyclonal antibody, Aff - Purified



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CNY 2,250.00


货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Applications WB
Recommend Dilution Western blot: 1:500~1:1000.
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Peptide sequence around phosphorylation site of tyrosine 205/222(K-G-Y(p)-T-K) derived from Human MAPK1/3 (KLH-conjugated)
Specificity The antibody detects endogenous levels of MAPK1/3 only when phosphorylated at tyrosine 205/222.
Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
State: Aff - Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Affinity chromatography using epitope-specific peptide
Conjugation Unconjugated
Storage Condition Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Predicted Protein Size 44 kDa
Gene Name mitogen-activated protein kinase 1
Background The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
Synonyms Mitogen-activated protein kinase 1, Mitogen-activated protein kinase 3, p42-MAPK, ERT1, ERT2, PRKM3, PRKM2, MAP kinase 2, MAPK2, MAPK1
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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