CD41-CD61 Complex Mouse Monoclonal Antibody [Clone ID: P2]

CAT#: BM2543

CD41-CD61 Complex mouse monoclonal antibody, clone P2, Azide Free



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CNY 16,800.00


货期*
5周

规格
    • 200 ug

Cited in 1 publication.

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Specifications

Product Data
Clone Name P2
Applications ELISA, FC, FN, IHC, IP
Recommend Dilution ELISA.
Immunoprecipitation.
Functional Assays. 
Fluorescence Microscopy or Flow Cytometry: 
2 µg / 5x106 platelets/test.
Immunohistochemistry (Only suitable on Frozen Sections or Cell Smears): 
1/50-1/100. 
Not recommended for use in Western blot.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Human platelets
Specificity Reacts with gpIIb in the intact complex with gpIIIa, but not with IIb or IIIa, separately.
Inhibits platelet aggregation induced by thrombin, collagen and ADP.
The Molecular weight of the recognized antigen is 135kDa/95kDa.
Formulation PBS buffer
State: Azide Free
State: Lyophilized purified Ig fraction
Stabilizer: 1 mg/ml BSA
Preservative: None
Reconstitution Method Restore with 1 ml distilled water.
Concentration N/A
Conjugation Unconjugated
Storage Condition Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month 
or (in aliquots) at -20°C long term. 
The addition of 0.09% (w/v) Sodium Azide is recommended for storage of the reconstituted form for up to one month at 2-8°C.
Avoid repeated freezing and thawing.
Background Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.
Synonyms GPIIb-IIIa, ITGA2B, GP2B, ITGAB, Platelet membrane glycoprotein IIb, GPalpha IIb, GPIIb, GP3A, CD41, CD61, Integrin alpha-IIb, Integrin beta-3, ITGB3
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (1)

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