Hepatitis B Core Antigen / HBcAg (ayw, 135-140) Mouse Monoclonal Antibody [Clone ID: 13A9]

Specifications

Product Data
Clone Name	13A9
Applications	ELISA, WB
Recommend Dilution	ELISA. Western blot. Strongly recognizes WHc (but not DHBc) in ELISA and immunoblot. Immunoprecipitation of in vitro-translated core and pre-core proteins.
Reactivity	Hepatitis B Virus
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant HBcAg core antigen (ayw)
Specificity	This antibody reacts to HBcAg core antigen (amino acids 135-140). Reacts with synthetic HBc peptides.
Formulation	PBS, pH 7.4 Label: Biotin State: Liquid purified IgG
Purification	Protein A chromatography
Conjugation	Biotin
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Background	Hepatitis B Virus Core Antigen (HBcAg) is part of the infectious virion containing an inner "core particle" enclosing the viral genome. The icosahedral core particle contains 180 or 240 copies of the core protein. HBcAg is one of the three major clinical antigens of hepatitis B virus but disappears early in the course of infection. The hepatitis B virus core antigen (HBcAg) is a highly immunogenic subviral particle and functions as both a T-cell-dependent and a T-cell-independent antigen. Therefore, HBcAg may be a promising candidate target for therapeutic vaccine control of chronic HBV infection.
Synonyms	HBV Capsid protein, HBV Core protein, p21.5
Reference Data

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