Hepatitis B Core Antigen / HBcAg (ayw, 135-140) Mouse Monoclonal Antibody [Clone ID: 13A9]

Specifications

Product Data
Clone Name	13A9
Applications	ELISA, IF, IP, WB
Recommend Dilution	Immunofluorescence, ELISA, Western blot, Immunoprecipitation of in vitro-translated core and pre-core proteins.
Reactivity	Hepatitis B Virus
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant HBcAg core antigen (ayw)
Specificity	This antibody is specific for HBcAg core antigen. Amino acids 135-140 core antigen. Reacts with synthetic HBc peptides. Strongly recognizes Woodchuck Hepatitis virus core (WHc), but not Duck Hepatitis B virus core (DHBc) in ELISA and immunoblot.
Formulation	PBS, pH 7.4 without preservatives. State: Azide Free State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Protein A chromatography.
Conjugation	Unconjugated
Storage Condition	Store the antibody at 2-8°C for one month or at -20°C for longer. Avoid repeated freezing and thawing.
Background	Hepatitis B Virus Core Antigen (HBcAg) is part of the infectious virion containing an inner "core particle" enclosing the viral genome. The icosahedral core particle contains 180 or 240 copies of the core protein. HBcAg is one of the three major clinical antigens of hepatitis B virus but disappears early in the course of infection. The hepatitis B virus core antigen (HBcAg) is a highly immunogenic subviral particle and functions as both a T-cell-dependent and a T-cell-independent antigen. Therefore, HBcAg may be a promising candidate target for therapeutic vaccine control of chronic HBV infection.
Synonyms	HBV Capsid protein, HBV Core protein, p21.5
Reference Data

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