Cytokeratin 14 (KRT14) Mouse Monoclonal Antibody [Clone ID: RCK107]

Specifications

Product Data
Clone Name	RCK107
Applications	FC, IF, IHC, WB
Recommend Dilution	Immunocytochemistry. Immunohistochemistry on Frozen sections. Flow cytometry. Immunoblotting. Recommended Dilutions: 1/100-1/200 for Flow Cytometry, and for Immunohistochemistry with avidin-biotinylated Horseradish Peroxidase complex (ABC) as detection reagent and 1/100-1/1000 for Immunoblotting applications.
Reactivity	Canine, Human, Porcine, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Cytoskeletal preparation of TR146 epithelial cells.
Specificity	RCK107 reacts exclusively with Cytokeratin 14 which is present in basal cell compartments of stratified and combined epithelia.
Formulation	PBS with 0.09% Sodium Azide as preservative. State: Purified State: Liquid purified IgG fraction
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freeze-thaw cycles.
Gene Name	keratin 14
Database Link	Entrez Gene 3861 Human UniProt ID P02533
Background	Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9-7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
Synonyms	Cytokeratin-14, CK14, Keratin 14, K14, KRT14
Reference Data

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