KRT13 Mouse Monoclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	Immunoblotting. Immunofluorescence. Immunohistochemistry on Frozen Sections: 1/5-1/25 (±1/20), preferable in PBS. Immunohistochemistry on Paraffin Sections: 1/10 after TUF treatment.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Cytokeratin purified from Human esophagus
Specificity	This Monoclonal Antibody Clone 2D7 does stain non-cornifying squamous epithelium. In Immunoblotting experiments the antibody recognizes only Keratin 13 (54kD) and does not show any cross reactivity with other keratins. The antibody is a useful Marker for histopathology. Frozen sections give excellent results in immunoperoxidase and immunofluorescence tests. Cross reactivity: Vimentin : not detectable Desmin : not detectable GFAP : not detectable Neurofilament : not detectable.
Formulation	State: Supernatant State: Liquid Culture Supernatant Preservative: 10mM Sodium Azide, FCS
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C.
Gene Name	keratin 13
Database Link	Entrez Gene 3860 Human UniProt ID P13646
Background	Cytokeratin 13 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus.
Synonyms	CK-13, CK13, Keratin-13, KRT13, K13, KRT-13
Reference Data

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