Hepatitis B Surface Antigen / HBsAg (ad/ay) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, Ie, IF
Recommend Dilution	Suitable for use in ELISA and IEP.
Reactivity	Hepatitis B Virus
Host	Goat
Clonality	Polyclonal
Immunogen	Mixture of subtypes ad & ay. Hepatitis B surface antigen purified from human serum.
Specificity	Purified surface antigen. Monospecific, reacts only with Hepatitis B surface antigen including the pre-S1 epitope. Non-reactive with normal human serum.
Formulation	0.01 M PBS, pH 7.2, containing 10 mg/ml BSA as stabilizer and 0.09 % Sodium azide as preservative. Label: FITC State: Liquid purified Ig fraction. Label: Highly purified Isomer I of fluorescein isothiocyanate. Care is taken to ensure complete removal of any free fluorescein from the final product
Concentration	lot specific
Conjugation	FITC
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Background	Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.
Synonyms	HBV surface antigen, Hepatitis B Virus
Reference Data

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