Rubella virus (Strain HPV77) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	Suitable for immunohistochemical, immunoblotting and EIA applications. Starting range recommended for : Immunochemistry and blotting: 1:20-1:200 Enzyme Immunoassays: 1:200-1:1,000 Indirect immunofluorescence: >1:2560.
Reactivity	Rubella Virus
Host	Goat
Clonality	Polyclonal
Immunogen	Strain HPV77
Specificity	Recognizes purified virions. Uninfected cell reactivity is negative vs. Vero cells by indirect immunofluorescence.
Formulation	0.01 M PBS, pH 7.2 with 0.002% Thimerosal as preservative and 10 mg/ml Bovine Serum Albumin as stabilizer. Label: HRP State: Liquid purified Ig fraction. Label: Highly purified preparation of horseradish peroxidase (RZ>3. Care is taken to ensure adequate conjugation while preserving maximum enzyme activity. Free enzyme is absent
Concentration	lot specific
Purification	Immunoaffinity chromatography.
Conjugation	HRP
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Background	Rubella virus is the only member of the Rubrivirus genus of the Togavirus family. Unlike most Togaviruses it is NOT arthropod borne, but is acquired via the respiratory route. It causes German measles ( a mild contagious eruptive disease, capable of producing congenital defects in infants born to mothers infected during the first three months of pregnancy). Rubella virus is an enveloped positive-strand RNA virus. The genome encodes two open reading frames (ORFs): the 5'-proximal ORF encodes viral nonstructural proteins (NSP) that are responsible for viral genome replication, while the 3'-proximal ORF encodes three virion structural proteins (SP), the capsid protein (CP), and the two envelope glycoproteins, E2 and E1. During virus assembly, the capsid interacts with genomic RNA to form nucleocapsids. The rubella virus (RV) structural proteins: capsid, E2, and E1 are synthesized as a polyprotein precursor. The signal peptide that initiates translocation of E2 into the lumen of the endoplasmic reticulum remains attached to the carboxy terminus of the capsid protein after cleavage by signal peptidase.
Synonyms	German measles
Reference Data

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