ITM2B Chicken Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Western blot Not recommended for Immunohistochemistry.
Reactivity	Human
Host	Chicken
Clonality	Polyclonal
Immunogen	Peptide coupled to carrier protein. Amino terminal sequence of BRI protein (ITM2B)
Specificity	This antibody has been developed against the amino terminal sequence of BRI protein (ITM2B).
Formulation	PBS, pH 7.2 State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% Sodium Azide
Concentration	1.0 mg/ml
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	integral membrane protein 2B
Database Link	Entrez Gene 9445 Human UniProt ID Q9Y287
Background	BRI protein (ITM2B) is a type-II single spanning transmembrane protein found in brain and other tissues. Mutation of the BRI gene with concomitant elongation of the carboxy terminus and its cleavage by the protease furin has been shown to lead to deposition of a protein fragment that may be involved in the pathogenesis of familial British dementia.
Synonyms	ITM2B, BRI, BRI2, Integral membrane protein 2B, Transmembrane protein BRI
Reference Data

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