Antithrombin III (SERPINC1) Mouse Monoclonal Antibody [Clone ID: OTI8D5]

Specifications

Product Data
Clone Name	OTI8D5
Applications	FC, WB
Recommend Dilution	FLOW 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human SERPINC1 (NP_000479) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	52.6 kDa
Gene Name	serpin family C member 1
Database Link	NP_000479 Entrez Gene 11905 MouseEntrez Gene 304917 RatEntrez Gene 462 Human UniProt ID P01008
Background	Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin.
Synonyms	AT3; AT3D; ATIII; THPH7
Reference Data
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	Complement and coagulation cascades

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