DOK2 Mouse Monoclonal Antibody [Clone ID: OTI2D10]

Specifications

Product Data
Clone Name	OTI2D10
Applications	WB
Recommend Dilution	WB 1:200~500
Reactivity	Human, Dog, Rat, Monkey, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human DOK2(NP_003965) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	45.2 kDa
Gene Name	docking protein 2
Database Link	NP_003965 Entrez Gene 13449 MouseEntrez Gene 290361 RatEntrez Gene 486133 DogEntrez Gene 706317 MonkeyEntrez Gene 9046 Human UniProt ID O60496
Background	The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq]
Synonyms	p56DOK; p56dok-2
Reference Data
Protein Families	Druggable Genome

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