Syntenin (SDCBP) Mouse Monoclonal Antibody [Clone ID: OTI2H6]

Specifications

Product Data
Clone Name	OTI2H6
Applications	IHC, WB
Recommend Dilution	WB 1:500~2000, IHC 1:150
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human SDCBP(NP_005616) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	32.3 kDa
Gene Name	syndecan binding protein
Database Link	NP_005616 Entrez Gene 53378 MouseEntrez Gene 83841 RatEntrez Gene 6386 Human UniProt ID O00560
Background	The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]
Synonyms	MDA-9; MDA9; ST1; SYCL; TACIP18
Reference Data
Protein Families	Druggable Genome, Transmembrane

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