Amyloid Precursor Protein (APP) Mouse Monoclonal Antibody [Clone ID: OTI1E6]
CAT#: CF504968
Carrier-free (BSA/glycerol-free) APP mouse monoclonal antibody, clone OTI1E6 (formerly 1E6)
Formulation: Standard
View other "OTI1E6" antibodies (6)
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CNY 3,999.00
Specifications
Product Data | |
Clone Name | OTI1E6 |
Applications | IF, WB |
Recommend Dilution | WB 1:2000, IF 1:100 |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human APP(NP_000475) produced in HEK293T cell. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 85.1 kDa |
Gene Name | amyloid beta precursor protein |
Database Link | |
Background | This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq] |
Synonyms | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2 |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Alzheimer's disease |
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抗体相关资料 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA504968 | APP (Amyloid beta precursor protein) mouse monoclonal antibody, clone OTI1E6 (formerly 1E6) |
CNY 1,999.00 |
|
TA504968AM | APP mouse monoclonal antibody,clone 1E6, Biotinylated |
CNY 3,990.00 |
|
TA504968BM | APP mouse monoclonal antibody,clone 1E6, HRP conjugated |
CNY 3,990.00 |
|
TA504968S | APP (Amyloid beta precursor protein) mouse monoclonal antibody, clone OTI1E6 (formerly 1E6) |
CNY 800.00 |
|
TA600256 | APP mouse monoclonal capture antibody, validated for Luminex assays |
CNY 2,600.00 |
|
TA700256 | APP biotinylated mouse monoclonal detection antibody, validated for Luminex assays |
CNY 2,700.00 |
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