CMPK1 Mouse Monoclonal Antibody [Clone ID: OTI2B2]

Specifications

Product Data
Clone Name	OTI2B2
Applications	IF, IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150, IF 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human CMPK1(NP_057392) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	25.7 kDa
Gene Name	cytidine/uridine monophosphate kinase 1
Database Link	NP_057392 Entrez Gene 66588 MouseEntrez Gene 298410 RatEntrez Gene 51727 Human UniProt ID P30085
Background	Uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP (dCMP), resulting in the formation of ADP and the corresponding nucleoside diphosphate. These nucleoside diphosphates are required for cellular nucleic acid synthesis (Liou et al., 2002 [PubMed 11912132]). [supplied by OMIM]
Synonyms	CK; CMK; CMPK; UMK; UMP-CMPK; UMPK
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Metabolic pathways, Pyrimidine metabolism

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