HGS Mouse Monoclonal Antibody [Clone ID: OTI3H7]

Specifications

Product Data
Clone Name	OTI3H7
Applications	IF, WB
Recommend Dilution	WB 1:4000, IF 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human HGS(NP_004703) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	86 kDa
Gene Name	hepatocyte growth factor-regulated tyrosine kinase substrate
Database Link	NP_004703 Entrez Gene 15239 MouseEntrez Gene 56084 RatEntrez Gene 9146 Human UniProt ID O14964
Background	The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation. [provided by RefSeq, Dec 2010]
Synonyms	HRS
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Endocytosis

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