DRP1 (DNM1L) Mouse Monoclonal Antibody [Clone ID: OTI4B5]

Specifications

Product Data
Clone Name	OTI4B5
Applications	IHC, WB
Recommend Dilution	WB:1:1000; IHC:1:150
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human DNM1L(NP_036192) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	81.7 kDa
Gene Name	dynamin 1 like
Database Link	NP_036192 Entrez Gene 74006 MouseEntrez Gene 114114 RatEntrez Gene 10059 Human UniProt ID O00429
Background	The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated. [provided by RefSeq, Jul 2008]
Synonyms	DLP1; DRP1; DVLP; DYMPLE; EMPF; EMPF1; HDYNIV
Reference Data
Protein Pathways	Endocytosis, Fc gamma R-mediated phagocytosis

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