AMPK beta 2 (PRKAB2) Mouse Monoclonal Antibody [Clone ID: OTI4H4]
CAT#: CF808333
Carrier-free (BSA/glycerol-free) PRKAB2 mouse monoclonal antibody, clone OTI4H4 (formerly 4H4)
Formulation: Standard
View other "OTI4H4" antibodies (4)
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CNY 3,999.00
Specifications
Product Data | |
Clone Name | OTI4H4 |
Applications | WB |
Recommend Dilution | WB 1:2000 |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human PRKAB2 (NP_005390) produced in E.coli. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 30.1 kDa |
Gene Name | protein kinase AMP-activated non-catalytic subunit beta 2 |
Database Link | |
Background | The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013] |
Synonyms | MGC61468 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Adipocytokine signaling pathway, Hypertrophic cardiomyopathy (HCM), Insulin signaling pathway |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA808333 | PRKAB2 mouse monoclonal antibody, clone OTI4H4 (formerly 4H4) |
CNY 1,999.00 |
|
TA808333AM | PRKAB2 mouse monoclonal antibody, clone OTI4H4 (formerly 4H4), Biotinylated |
CNY 3,990.00 |
|
TA808333BM | PRKAB2 mouse monoclonal antibody, clone OTI4H4 (formerly 4H4), HRP conjugated |
CNY 3,990.00 |
|
TA808333S | PRKAB2 mouse monoclonal antibody, clone OTI4H4 (formerly 4H4) |
CNY 800.00 |
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