CD21 (CR2) Mouse Monoclonal Antibody [Clone ID: 1F8]

Specifications

Product Data
Clone Name	1F8
Applications	IHC
Recommend Dilution	Immunohistochemistry on paraffin embedded sections: use a dilution of 1:10-1:25 in an ABC method (30 minutes incubation at room temperature) Recommended positive control: Tonsil
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified receptor for the C3d fragment of the third complement component CR2, from human tonsil.
Specificity	This antibody reacts with CD21 antigen of MW 145 kD, present on the surface of mature B cells. Cellular Localization: Cell membrane
Formulation	State: Supernatant State: Liquid tissue culture supernatant containing sodium azide as preservative.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	complement component 3d receptor 2
Database Link	Entrez Gene 1380 Human UniProt ID P20023
Background	The antigen is present at high density on follicular dendritic cells. CD21 is involved in transmitting growth promoting signals to the interior of the B cell.
Synonyms	Complement receptor type 2, CR2, C3DR, C3d receptor, EBV Receptor, Dendritic Cell Marker
Reference Data

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