IL1 beta (IL1B) Mouse Monoclonal Antibody [Clone ID: S3F12]

Specifications

Product Data
Clone Name	S3F12
Applications	ELISA
Recommend Dilution	ELISA.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant human IL1 beta
Specificity	Reactive with natural and recombinant Human Interleukin-1 beta (IL1 beta). Does not show any cross reaction with recombinant Human IL1 alpha, recombinant Murine IL1 alpha or IL1 beta.
Formulation	0.01M PBS, pH 7.2 without preservatives. State: Purified State: Lyophilized purified IgG fraction.
Reconstitution Method	Restore with double distillated water to adjust the final concentration to 1.00 mg/ml
Concentration	lot specific
Purification	Affinity Chromatography on Protein G.
Conjugation	Unconjugated
Storage Condition	Store the antibody at -20°C. Avoid repeated freezing and thawing.
Gene Name	interleukin 1 beta
Database Link	Entrez Gene 3553 Human UniProt ID P01584
Background	Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types, and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin1 alpha (IL1 alpha) and interleukin1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25% homology in their amino acid sequence.
Synonyms	IL-1 beta, IL1B, IL1 beta, IL1F2, Catabolin
Reference Data
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	Alzheimer's disease, Apoptosis, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Graft-versus-host disease, Hematopoietic cell lineage, MAPK signaling pathway, NOD-like receptor signaling pathway, Prion diseases, Toll-like receptor signaling pathway, Type I diabetes mellitus

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