GCSF Receptor (CSF3R) Mouse Monoclonal Antibody [Clone ID: S-1390]

Specifications

Product Data
Clone Name	S-1390
Applications	ELISA, WB
Recommend Dilution	ELISA. Immunoblotting: Recognizes denatured G-CSFR following SDS-PAGE and blotting of 200 ug of cell lysate or following immunoprecipitation with polyclonal antibody followed by immunoblotting.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant MBP-GCSFR fusion protein.
Specificity	Reactive with G-CSFR and does not cross-react with MBP or BSA (Bovine Serum Albumin).
Formulation	0.01M PBS, pH 7.2 without preservatives. State: Purified State: Lyophilized purified IgG fraction.
Reconstitution Method	Restore with Double distillated water to adjust the final concentration to 1.00 mg/ml
Concentration	lot specific
Purification	Affinity Chromatography on Protein G.
Conjugation	Unconjugated
Storage Condition	Store the antibody at -20°C. Avoid repeated freezing and thawing.
Gene Name	colony stimulating factor 3 receptor
Database Link	Entrez Gene 1441 Human UniProt ID Q99062
Background	The protein encoded by the GCSF Receptor gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Four transcript variants encoding four different isoforms have been found for this gene, of which three are membrane-bound and the one secreted and soluble. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia.
Synonyms	G-CSF-R, GCSFR, GCSF Receptor, G-CSF Receptor
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Transmembrane
Protein Pathways	Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway, Pathways in cancer

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