CD8A Mouse Monoclonal Antibody [Clone ID: 144B]

Specifications

Product Data
Clone Name	144B
Applications	IHC
Recommend Dilution	Immunohistochemistry on paraffin embedded sections: diluted of 1:25-1:50 in an ABC method (60 minutes at room temperature or overnight at 4°C).  High temperature antigen retrieval with 10 mM citrate buffer pH 6.0 prior staining is required.  Positive control: Tonsil
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic peptide comprising of 13 C terminal amino acids of the cytoplasmic domain of CD8 molecule.
Specificity	This antibody reacts specifically with a 32 kD protein similar to CD8 molecule. Cellular localization: Cell membrane
Formulation	Tissue culture supernatant containing sodium azide as a preservative. State: Supernatant State: Liquid.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C.
Gene Name	CD8a molecule
Database Link	Entrez Gene 925 Human UniProt ID P01732
Background	This antibody stains cytotoxic/suppressor T cells and shows a staining patterns similar to clustered CD8 monoclonal antibodies.
Synonyms	CD8 alpha chain, CD8A, MAL
Reference Data
Protein Families	Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Transmembrane
Protein Pathways	Antigen processing and presentation, Cell adhesion molecules (CAMs), Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway

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