Chromogranin A (CHGA) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	Immunohistochemistry on Paraffin Embedded Sections: 1/20-1/50 in an ABC method (30-60 minutes at room temperature) Recommended Positive Control: Pancreas.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	C-terminal half of chromogranin A was purified from urine of patients with carcinoid syndrome.
Specificity	This antibody reacts with human Chromogranin A in the neuroendocrine cells and neural tissues. It does not recognizes the epitopes located on the N-terminal half of the chromogranin A molecule. Cellular Localization: Cytoplasmic.
Formulation	10 mM Citrate buffer, pH 6.0 containing Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	chromogranin A
Database Link	Entrez Gene 1113 Human UniProt ID P10645
Background	Chromogranin A (a protein of 439 amino acids which is encoded on chromosome 14) is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, phenochromocytomas, paragangliomas, and other neuroendocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.
Synonyms	Chromogranin-A, CgA, CHGA, SP-I
Reference Data

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