CD23 Rabbit Monoclonal Antibody [Clone ID: SP23]

Specifications

Product Data
Clone Name	SP23
Applications	IHC
Recommend Dilution	Immunohistochemistry on Formalin-Fixed Paraffin Embedded Sections: Use at 1/100 dilution in an ABC method for 30 minutes at room temperature. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Recommended Positive Control: Tonsil.
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Immunogen	Recombinant protein encoding Human CD23 48-248 aa
Specificity	This antibody recognizes CD23. Cellular Localization: Cell membrane
Formulation	State: Supernatant State: Liquid Tissue Culture Supernatant containing Sodium Azide as preservative.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	Fc fragment of IgE receptor II
Database Link	Entrez Gene 2208 Human UniProt ID P06734
Background	CD23 is a 45kDa glycoprotein, which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma
Synonyms	Fc-epsilon-RII, FCER2, CD23A, FCE2, IGEBF
Reference Data

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