Cd40 Rat Monoclonal Antibody [Clone ID: 3/23]

CAT#: SM008R

Cd40 rat monoclonal antibody, clone 3/23, PE



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CNY 6,369.00


货期*
4周

规格
    • 100 Tests

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Specifications

Product Data
Clone Name 3/23
Applications FC
Recommend Dilution Flow Cytometry: Use 10 µl of diluted antibody to label 10e6 cells in 100 µl.
The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors.
Reactivity Mouse
Host Rat
Clonality Monoclonal
Immunogen Extracellular Domain of Mouse CD40 and the Fc portion of Human IgG1. Spleen cells from immunised LOU/c rats were fused with cells of the Ag8 mouse myeloma cell line.
Specificity This antibody recognises CD40 and stains most mature mouse B cells. T cells are unlabelled.
Formulation PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer.
Label: PE
State: Lyophilized purified IgG fraction.
Label: R. Phycoerythrin (RPE)
Reconstitution Method Restore with distilled water:
SM008R with 1.0 ml.
SM008RT with 0.25 ml
SM008RX with 5.0 ml
Concentration lot specific
Purification Affinity Chromatography on Protein G.
Conjugation PE
Storage Condition Prior to and following reconstitution store the antibody undiluted at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Gene Name CD40 antigen
Background CD40 is a costimulatory molecule of the TNF receptor superfamily and is expressed on many cell types, such as B cells, monocytes/macrophages, dendritic cells, endothelial cells, fibroblasts or vascular smooth muscle cells. Interaction of CD40 and its ligand CD154 (CD40L) is required for the generation of antibody responses to T-dependent antigens as well as for the development of germinal centers and memory B cells. In monocytes/macrophages CD40 engagement induces production of pro-inflammatory cytokines and chemokines. CD40-CD154 interactions are also critical for development of CD4 T cell-dependent effector functions. CD40 links innate and adaptive immune responses to bacterial stimuli and serves as an important regulator affecting functions of other costimulatory molecules.
Synonyms TNFRSF5, CDw40, Bp50
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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