CD8B Mouse Monoclonal Antibody [Clone ID: 2ST8.5H7]

Specifications

Product Data
Clone Name	2ST8.5H7
Applications	FC, IP, WB
Recommend Dilution	Western Blot. Immunoprecipitation. Flow Cytometry: Use 10 µl of neat-1/10 diluted CD8b antibody to label 10e6 cells in 100 µl.
Reactivity	Human, Monkey
Host	Mouse
Clonality	Monoclonal
Immunogen	Normal Human T lymphocytes.
Specificity	This antibody recognises the CD8 cell surface antigen. The antibody binds to the beta chain, recognising an epitope that is dependent upon expression of both CD8 alpha and CD8 beta.
Formulation	PBS, pH 7.4 with 1% BSA as stabilizer State: Purified State: Lyophilized purified IgG fraction.
Reconstitution Method	Restore with 0.2 ml distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. We recommend that the vial is gently mixed after reconstitution.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	CD8b molecule
Database Link	Entrez Gene 926 Human UniProt ID P10966
Background	The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
Synonyms	CD8B, CD8B1
Reference Data

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