CD14 Mouse Monoclonal Antibody [Clone ID: Tük4]
CAT#: SM1066PS
CD14 mouse monoclonal antibody, clone Tük4, Purified
Size: 200 ug
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CNY 4,499.00
货期*
4周
规格
Specifications
Product Data | |
Clone Name | Tük4 |
Applications | ELISA, FC, WB |
Recommend Dilution | Flow Cytometry: 1/50-1/200; use 5 µl of suggested working dilution to label 1x10e6 cells or 100 µl whole blood. ELISA. Western Blot. |
Reactivity | Bovine, Canine, Feline, Goat, Human, Mink, Monkey, Porcine, Rabbit, Sheep |
Host | Mouse |
Clonality | Monoclonal |
Specificity | This antibody recognises the CD14 cell surface antigen, expressed strongly by most peripheral blood monocytes and weakly on granulocytes. Clone Tuk4 has been shown to block SDF-induced chemotaxis of U937 cells in a dose-dependent manner. We recommend the use of SM1066LE for this purpose. |
Formulation | PBS containing 0.09% Sodium Azide as preservative. State: Purified State: Liquid purified IgG fraction. |
Concentration | lot specific |
Purification | Affinity chromatography on Protein G. |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Gene Name | CD14 molecule |
Database Link | |
Background | CD14 is a single copy gene encoding 2 protein forms: a 50 to 55 kDa glycosylphosphatidylinositol anchored membrane protein (mCD14) and a monocyte or liver derived soluble serum protein (sCD14) that lacks the anchor. Both molecules are critical for lipopolysaccharide (LPS) dependent signal transduction, and sCD14 confers LPS sensitivity to cells lacking mCD14. Increased sCD14 levels are associated with inflammatory infectious diseases and high mortality in gram negative shock. CD14 also appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes. |
Synonyms | CD14 |
Reference Data |
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