CD11a (ITGAL) Mouse Monoclonal Antibody [Clone ID: 38]

Specifications

Product Data
Clone Name	38
Applications	FC, FN, IHC, IP
Recommend Dilution	Flow cytometry: 1/50 - 1/100; use 5 µl of the suggested working dilution to label 10e6 cells in 100µl. Functional Assays. Immunoprecipitation. Immunohistochemistry on frozen sections. Recommended positive control tissue: Human Tonsil.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Specificity	This antibody recognises the integrin alphaL subunit, a 180kD glycoprotein expressed by all human leucocytes. The molecule is involved in cell-cell adhesion processes and binds to ICAM-1, 2 and 3. This antibody neutralises CD11a mediated adhesion.
Formulation	State: Azide Free State: Liquid purified IgG
Concentration	lot specific
Purification	Affinity chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store the antibody at -20°C. Avoid repeated freezing and thawing.
Gene Name	integrin subunit alpha L
Database Link	Entrez Gene 3683 Human UniProt ID P20701
Background	CD11a is a member of the integrin family of cell adhesion molecules. It is a glycoprotein expressed in combination with the CD18 beta chain. The complex is a member of the beta 2 integrin family. These molecules function in cell adhesion and specifically bind to CD54, ICAM2, ICAM3. CD11a is expressed on thymocytes, T and B lymphocytes, granulocytes, monocytes, and macrophages.
Synonyms	Integrin alpha-L, LFA1, LFA-1
Reference Data

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