CD32A (FCGR2A) Mouse Monoclonal Antibody [Clone ID: AT10]

Specifications

Product Data
Clone Name	AT10
Applications	FC
Recommend Dilution	Flow cytometry: Use 10µl of neat antibody to label 106 cells or 100 µl whole blood.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	K562 cell line. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.
Specificity	This antibody recognizes the Human CD32 antigen. Clone AT10 blocks the binding of IgG to Fc gamma R11 (See Larsson, M. et al. for details). SM1092LE is recommended for this purpose.
Formulation	PBS Label: PE State: Lyophilized purified IgG fraction Stabilizer: 1% BSA, 5% sucrose Preservative: 0.09% Sodium Azide Label: R. Phycoerythrin (RPE)
Reconstitution Method	SM1092R: Restore with 1.0 ml distilled water. SM1092RT: Restore with 0.25 ml distilled water.
Purification	Affinity Chromatography on Protein A
Conjugation	PE
Storage Condition	Store the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Gene Name	Fc fragment of IgG receptor IIa
Database Link	Entrez Gene 2212 Human UniProt ID P12318
Background	CD32 is a 40kD glycoprotein that acts as a low affinity receptor for IgG (also known as Fc gamma RII). The antigen mediates several functions including endocytosis, activation of secretion, cytotoxicity and immunomodulation.CD32 is expressed by B cells, monocytes, granulocytes and platelets.
Synonyms	Fc-gamma RII-a, Fc-gamma-RIIa, CDw32, FCGR2A, FCG2, FCGR2A1, IGFR2
Reference Data

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