HLA Class I ABC Mouse Monoclonal Antibody [Clone ID: W6/32]
CAT#: SM1222R
HLA Class I ABC mouse monoclonal antibody, clone W6/32, PE
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CNY 6,369.00
货期*
4周
规格
Cited in 2 publications. |
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Specifications
Product Data | |
Clone Name | W6/32 |
Applications | FC |
Recommend Dilution | Flow Cytometry: Use 10 μl of neat antibody to label 1x106 cells or 100 μl whole blood. This product is routinely tested in flow cytometry on human peripheral blood lymphocytes. |
Reactivity | Bovine, Feline, Human, Monkey, Primate |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Purified human tonsil lymphocyte membranes. Spleen cells from immunised BALB/c mice were fused with cells of the NS1/1 - Ag4.1 mouse myeloma cell line. |
Specificity | Antibody SM1222R recognises an antigenic determinant shared among products of the HLA A, B and C loci. Clone W6/32 recognises a conformational epitope, reacting with HLA class I alpha-3 and alpha-2 domains (See Ishitani, A. et al. for details). MHC class I glycoproteins are found on the surface of almost all nucleated somatic cells. |
Formulation | PBS Label: PE State: Lyophilized purified IgG fraction from Tissue Culture Supernatant Stabilizer: 1% BSA, 5% Sucrose Preservative: 0.09% Sodium Azide Label: R. Phycoerythrin (RPE) |
Reconstitution Method | Restore with 1ml distilled water |
Purification | Affinity Chromatography on Protein G |
Conjugation | PE |
Storage Condition | Prior to and following reconstitution store the antibody at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. |
Background | The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region. There are 3 major MHC class I proteins encoded by the HLA which are HLA A, HLA B and HLA C. These proteins are found on the surface of almost all nucleated somatic cells. |
Synonyms | MHC class I ABC, HLA Class 2 ABC |
Reference Data |
Citations (2)
The use of this Antibodies has been cited in the following citations: |
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Fibromodulin as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL), which allows expansion of specific CD8+ autologous T lymphocytes
,Mayr C, Bund D, Schlee M, Moosmann A, Kofler DM, Hallek M, Wendtner CM,
Blood
,PubMed ID 15471955
|
Transduction of CLL cells by CD40 ligand enhances an antigen-specific immune recognition by autologous T cells
,Mayr C, Kofler DM, B|ning H, Bund D, Hallek M, Wendtner CM,
Blood
,PubMed ID 16014560
|
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