Cytokeratin 14 (KRT14) Mouse Monoclonal Antibody [Clone ID: LL002]

Specifications

Product Data
Clone Name	LL002
Applications	FC, IF
Recommend Dilution	Immunofluorescence. Flow Cytometry: Use 10 µl of neat-1/10 diluted antibody to label 106 cells in 100 µl (Requires Membrane Permeabilisation).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Last 15 C-terminal residues of Human cytokeratin 14 conjugated to thyroglobulin.
Specificity	Recognizes Cytokeratin 14, a type I intermediate filament, expressed by stratifying epithelial cells and can be used to distinguish these cell types from simple epithelial cells, which do not express Cytokeratin 14. Mouse anti Cytokeratin 14, clone LL002 has been reported to be suitable for use in Western blotting (Alam et al. 2011).
Formulation	PBS Label: FITC State: Liquid purified IgG fraction from Tissue Culture Supernatant Stabilizer: 1% BSA Preservative: 0.09% Sodium Azide Label: Fluorescein Isothiocyanate Isomer 1
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	FITC
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Gene Name	keratin 14
Database Link	Entrez Gene 3861 Human UniProt ID P02533
Background	Keratin 14 is a member of the keratin family, the most diverse group of intermediate filaments. It is usually found as a heterotetramer with two molecules of keratin 5, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. Keratin 14 has been studied as a prognostic marker in breast cancer.
Synonyms	Cytokeratin-14, CK14, Keratin 14, K14, KRT14
Reference Data

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