B7-1 (CD80) Mouse Monoclonal Antibody [Clone ID: MEM-233]
CAT#: SM1742F
B7-1 (CD80) mouse monoclonal antibody, clone MEM-233, FITC
Conjugation: Unconjugated
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CNY 3,810.00
货期*
5周
规格
Cited in 1 publication. |
Specifications
Product Data | |
Clone Name | MEM-233 |
Applications | FC |
Recommend Dilution | Flow Cytometry analysis of human blood cells using 20 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Extracellular domain of human CD80 fused to human IgG1(Fc) |
Specificity | This antibody reacts with CD80 (B7-1), a 60 kDa single chain type I glycoprotein of immunoglobulin supergene family, expressed on professional antigen-presenting cells, such as dendritic cells, macrophages or activated B lymphocytes. |
Formulation | PBS containing 15 mM sodium azide Label: FITC State: Liquid purified Ig fraction Label: Conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. |
Conjugation | FITC |
Storage Condition | Store undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. |
Gene Name | CD80 molecule |
Database Link | |
Background | CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet; there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response. |
Synonyms | CD28LG, CD28LG1, LAB7, BB1, B7.1, B7-1 |
Reference Data |
Citations (1)
The use of this Antibodies has been cited in the following citations: |
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Activation of fractalkine/CX3CR1 by vascular endothelial cells induces angiogenesis through VEGF-A/KDR and reverses hindlimb ischaemia
,Ryu J, Lee CW, Hong KH, Shin JA, Lim SH, Park CS, Shim J, Nam KB, Choi KJ, Kim YH, Han KH,
Cardiovasc. Res.
,PubMed ID 18006432
[CD80]
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