B7-1 (CD80) Mouse Monoclonal Antibody [Clone ID: MEM-233]

CAT#: SM1742F

B7-1 (CD80) mouse monoclonal antibody, clone MEM-233, FITC

Conjugation: Unconjugated FITC



Need it in bulk or conjugated?
Get a free quote

CNY 3,810.00


货期*
5周

规格
    • 100 Tests

Cited in 1 publication.

Product images

Specifications

Product Data
Clone Name MEM-233
Applications FC
Recommend Dilution Flow Cytometry analysis of human blood cells using 20 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Extracellular domain of human CD80 fused to human IgG1(Fc)
Specificity This antibody reacts with CD80 (B7-1), a 60 kDa single chain type I glycoprotein of immunoglobulin supergene family, expressed on professional antigen-presenting cells, such as dendritic cells, macrophages or activated B lymphocytes.
Formulation PBS containing 15 mM sodium azide
Label: FITC
State: Liquid purified Ig fraction
Label: Conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions.
The reagent is free of unconjugated FITC and adjusted for direct use.
Conjugation FITC
Storage Condition Store undiluted at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Gene Name CD80 molecule
Background CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet; there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response.
Synonyms CD28LG, CD28LG1, LAB7, BB1, B7.1, B7-1
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (1)

Customer Reviews 
Loading...