B7-1 (CD80) Mouse Monoclonal Antibody [Clone ID: MEM-233]

CAT#: SM1742PS

B7-1 (CD80) mouse monoclonal antibody, clone MEM-233, Purified

Size: 100 ug 200 ug



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CNY 3,280.00


货期*
5周

规格
    • 100 ug

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Specifications

Product Data
Clone Name MEM-233
Applications FC, IP
Recommend Dilution Flow cytometry: 1-10 µg/ml.
Immunoprecipitation.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Extracellular domain of human CD80 fused to human IgG1(Fc)
Specificity The antibody reacts with CD80 (B7-1), a 60 kDa single chain type I glycoprotein of immunoglobulin supergene family, expressed on professional antigen-presenting cells, such as dendritic cells, macrophages or activated B lymphocytes.
Formulation Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
State: Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Protein-A affinity chromatography; purity: > 95% (by SDS-PAGE)
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C.
DO NOT FREEZE!
Gene Name CD80 molecule
Background CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet; there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response.
Synonyms CD28LG, CD28LG1, LAB7, BB1, B7.1, B7-1
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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